Exposure to phthalates during pregnancy can affect a newborn’s brain development study finds мальчик гей Phthalates — the synthetic chemicals used in everyday products for food packaging personal care toys and more — have been linked to abnormal neurological development in infants. Now scientists may have discovered a biological pathway for how this phenomenon could occur. Researchers found that in utero exposure to phthalates is linked with altered metabolism of neurotransmitters and amino acids involved in brain maturation according to a study published Wednesday in the journal Nature Communications. The report is the first to use untargeted metabolomics — the study of all small molecules or metabolites in a biological system — to connect a mother’s phthalate exposure to a newborn’s metabolites and those metabolites to neurological development said senior study author Dr. Donghai Liang via email. “This represents an important step forward in understanding how prenatal chemical exposures shape infant development at the molecular level” added Liang an associate professor of environmental health at Emory University’s Rollins School of Public Health in Atlanta. First introduced in the 1920s phthalates are used to make plastics softer and more flexible primarily in polyvinyl chloride PVC products such as vinyl flooring medical devices children’s toys food packaging or shower curtains. The chemicals also help lubricate substances and carry fragrances in various personal care products including deodorant; nail polish; perfumes; hair gels sprays or shampoos; soaps; and body lotions. Phthalates are also endocrine disruptors that have been linked to preterm birth infant genital abnormalities childhood obesity asthma cancer cardiovascular issues and low sperm count and testosterone in men. “We conducted this study because phthalates are everywhere in our daily lives” Liang said hence their nickname “everywhere chemicals.” Harming infant health The findings are based on mother-newborn pairs enrolled in the Atlanta African American Maternal-Child Cohort between 2016 and 2018. In urine samples collected from 216 mothers between eight weeks and 14 weeks of gestation at visit one and 145 participants between 24 and 30 weeks’ gestation at visit two the authors measured eight phthalate metabolites. Participants were around age 24 on average and their levels of some phthalate metabolites were higher than the average determined by the National Health and Nutrition Examination Survey. Within a day or two of birth the authors collected the babies’ blood via a heel stick. The team found prenatal phthalate levels were associated with lower levels of tyrosine an amino acid and precursor to the thyroid hormone thyroxine. Thyroxine was also abnormally low in those with in utero phthalate exposure and low thyroxine has been previously associated with greater vulnerability to illness and neurodevelopmental issues in newborns the authors said. Tyrosine is also a precursor to the neurotransmitters dopamine norepinephrine and epinephrine all of which partly contribute to the body’s fight-or-flight response. Low levels of these neurotransmitters can lead to various problems including anxiety depression and trouble focusing. Prenatal phthalate exposure was also linked with lower levels of the essential amino acid tryptophan which converts into 5-hydroxytryptophan or 5-HTP which then turns into serotonin. Both 5-HTP and serotonin were also low. Serotonin has several critical roles in the body including mood regulation sleep learning memory digestion and the body’s response to stress. Previous research has linked low serotonin with mood disorders such as depression and anxiety sleep problems and digestive issues.
The voice of ‘White Lotus’ star Walton Goggins is the lullaby we didn’t know we needed jumper exchange While his “White Lotus” character Rick has been the source of some stress this season Walton Goggins is here to soothe us into a state of dreamy sleep to make up for it. The actor has partnered with relaxation and meditation app Calm for one of their famed Sleep Stories lending his smoky voice to a fable titled “The Yard Sale.” Goggins announced the Sleep Story on his verified Instagram on Tuesday writing “A friend once said to me the first question you ask someone shouldn’t be ‘How are you?’ but rather ‘How did you sleep last night?’ I agree.” The post included an excerpt from the story in which Goggins is heard languidly instructing listeners to relax their bodies and get into bed. “You could even climb into a hammock” he added. “I wouldn’t do that because I’ve never gracefully got in or out of one.” In the caption the actor also wrote that he “wanted to create a Sleep Story that feels dreamlike helping people slow their minds down by wandering through a yard sale which happens to be one of my favorite things to do uncovering hidden treasures.” “It’s the Walton Goggins version of counting sheep. I hope you enjoy” he added. Other celebrities who have read bedtime stories in the hopes of putting audiences to sleep include Dolly Parton and the late Jimmy Stewart whose voice was featured in a Calm Christmas Sleep Story in 2023 thanks to generative AI technology. Goggins currently stars on “The White Lotus” where his character is often the most stressed out and tortured of the ensemble at one point setting a slew of snakes free.
“You have a government that is reckless about what is going to happen to Guyana” said Melinda Janki an international lawyer in Guyana who is handling several lawsuits against Exxon. It’s pursuing “a supposed course of development that is actually backward and destructive” she told CNN. kelpdao And while plenty of Guyanese people welcome the new oil industry some say Guyana’s startling economic statistics do not reflect a real-world prosperity for ordinary people many of whom are struggling with the higher prices accompanying the oil boom. Inflation rose 6.6 in 2023 with prices of some foods shooting up much more rapidly. “Since the oil extraction began in Guyana we have noticed that our cost of living has gone sky high” said Wintress White of Red Thread a non-profit that focuses on improving living conditions for Guyanese women. “The money is not trickling down to the masses” she told CNN. CNN contacted President Ali the Ministry of Natural Resources and the Ministry of Finance for comment but received no response. Guyana a former Dutch then British colony which gained independence in 1966 is one of only a handful of countries that is a “carbon sink” meaning it stores more planet-heating pollution than it produces. This is due to its vast rainforest; trees remove carbon dioxide from the atmosphere as they grow. The country has protected its biodiversity where others have destroyed theirs President Ali said in a BBC interview last year. In 2009 the country signed an agreement with Norway which promised Guyana more than 250 million to preserve its 18.5 million hectares or nearly 46 million acres of forests. Ali insists the country can balance climate leadership and fossil fuel exploitation. The new oil wealth will allow Guayana to develop including building climate adaptations such as sea walls he has said. He has also pointed to the continued failures of wealthy countries already grown rich on their own fossil fuels to help poorer countries with climate finance. But there are concerns Guyana could fall victim to the “resource curse” in which vast new wealth ?can actually make life worse for those who live there.
“Every morning I come downstairs and he’s already done the dishwasher he’s already packed his lunch and he’s ready to go” Ruthe’s father Ben tells CNN Sports. “He’s just a disciplined kid. He goes to bed early he looks after himself he eats well he looks after his sister. He’s just a good kid around the house in all ways really. We’re very lucky.” pendle Ruthe is next due to compete in the 1500 meters at the Maurie Plant Meet in Melbourne on Saturday and one target time to aim for will be his dad’s fastest time of 3:41.22 – three hundredths of a second faster than Ruthe’s current personal best. But he still has a way to go before he can call himself the most decorated runner in his family. Dad Ben and mom Jess are both former national champions who represented New Zealand on the world stage while his maternal grandparents won European championship medals for Great Britain. His grandmother Rosemary Stirling arguably had the most impressive achievement: an 800m Commonwealth Games title from 1970. Despite his family pedigree Ruthe was never under any pressure to take running seriously. His parents in fact didn’t allow him or his sister Daisy to train at all until they were 13 never wanting their identities to be tied solely to running. “It feels like it’s the right decision about now” says Ben. But as he gradually starts to realize his potential Ruthe when pushed admits to having big goals in the sport. “If I had to pick one thing definitely Olympic gold” he says. “I feel like that’s most runners’ dream and the biggest thing you can actually win. So that’ll definitely be the top of my bucket list.” The 2032 Olympics in Brisbane Ruthe adds would be a nice target. And as for the Los Angeles Games in three years’ time? “I’d actually love to try and qualify for LA 28” he says. “I feel like that’ll be a tough goal. But if I do that I’ll be really happy.” Already Ruthe’s name is being mentioned in the same breath as Norway’s Jakob Ingebrigtsen the most successful middle-distance of this generation. It was his record as the youngest-ever four-minute miler that Ruthe took last week and the New Zealander also beat Ingebrigtsen’s 1500m record for a 15-year-old earlier this year. Ingebrigtsen’s success Ruthe says has given him hope that he too can “have a good future” in the sport. But his biggest source of motivation comes not from the two-time Olympic champion but from those closest to him – his training group led by coach Craig Kirkwood and athlete Sam Tanner. The pair were instrumental in Ruthe’s recent mile time of 3:58.35 and it was five-time national champion Tanner who paced him perfectly around four laps of the track on his way to the record.
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Recomendo o jogo a todos Fortune Tiger
Recomendo o jogo a todos Fortune Tiger
Exposure to phthalates during pregnancy can affect a newborn’s brain development study finds мальчик гей Phthalates — the synthetic chemicals used in everyday products for food packaging personal care toys and more — have been linked to abnormal neurological development in infants. Now scientists may have discovered a biological pathway for how this phenomenon could occur. Researchers found that in utero exposure to phthalates is linked with altered metabolism of neurotransmitters and amino acids involved in brain maturation according to a study published Wednesday in the journal Nature Communications. The report is the first to use untargeted metabolomics — the study of all small molecules or metabolites in a biological system — to connect a mother’s phthalate exposure to a newborn’s metabolites and those metabolites to neurological development said senior study author Dr. Donghai Liang via email. “This represents an important step forward in understanding how prenatal chemical exposures shape infant development at the molecular level” added Liang an associate professor of environmental health at Emory University’s Rollins School of Public Health in Atlanta. First introduced in the 1920s phthalates are used to make plastics softer and more flexible primarily in polyvinyl chloride PVC products such as vinyl flooring medical devices children’s toys food packaging or shower curtains. The chemicals also help lubricate substances and carry fragrances in various personal care products including deodorant; nail polish; perfumes; hair gels sprays or shampoos; soaps; and body lotions. Phthalates are also endocrine disruptors that have been linked to preterm birth infant genital abnormalities childhood obesity asthma cancer cardiovascular issues and low sperm count and testosterone in men. “We conducted this study because phthalates are everywhere in our daily lives” Liang said hence their nickname “everywhere chemicals.” Harming infant health The findings are based on mother-newborn pairs enrolled in the Atlanta African American Maternal-Child Cohort between 2016 and 2018. In urine samples collected from 216 mothers between eight weeks and 14 weeks of gestation at visit one and 145 participants between 24 and 30 weeks’ gestation at visit two the authors measured eight phthalate metabolites. Participants were around age 24 on average and their levels of some phthalate metabolites were higher than the average determined by the National Health and Nutrition Examination Survey. Within a day or two of birth the authors collected the babies’ blood via a heel stick. The team found prenatal phthalate levels were associated with lower levels of tyrosine an amino acid and precursor to the thyroid hormone thyroxine. Thyroxine was also abnormally low in those with in utero phthalate exposure and low thyroxine has been previously associated with greater vulnerability to illness and neurodevelopmental issues in newborns the authors said. Tyrosine is also a precursor to the neurotransmitters dopamine norepinephrine and epinephrine all of which partly contribute to the body’s fight-or-flight response. Low levels of these neurotransmitters can lead to various problems including anxiety depression and trouble focusing. Prenatal phthalate exposure was also linked with lower levels of the essential amino acid tryptophan which converts into 5-hydroxytryptophan or 5-HTP which then turns into serotonin. Both 5-HTP and serotonin were also low. Serotonin has several critical roles in the body including mood regulation sleep learning memory digestion and the body’s response to stress. Previous research has linked low serotonin with mood disorders such as depression and anxiety sleep problems and digestive issues.
Recomendo o jogo a todos Tiger
The voice of ‘White Lotus’ star Walton Goggins is the lullaby we didn’t know we needed jumper exchange While his “White Lotus” character Rick has been the source of some stress this season Walton Goggins is here to soothe us into a state of dreamy sleep to make up for it. The actor has partnered with relaxation and meditation app Calm for one of their famed Sleep Stories lending his smoky voice to a fable titled “The Yard Sale.” Goggins announced the Sleep Story on his verified Instagram on Tuesday writing “A friend once said to me the first question you ask someone shouldn’t be ‘How are you?’ but rather ‘How did you sleep last night?’ I agree.” The post included an excerpt from the story in which Goggins is heard languidly instructing listeners to relax their bodies and get into bed. “You could even climb into a hammock” he added. “I wouldn’t do that because I’ve never gracefully got in or out of one.” In the caption the actor also wrote that he “wanted to create a Sleep Story that feels dreamlike helping people slow their minds down by wandering through a yard sale which happens to be one of my favorite things to do uncovering hidden treasures.” “It’s the Walton Goggins version of counting sheep. I hope you enjoy” he added. Other celebrities who have read bedtime stories in the hopes of putting audiences to sleep include Dolly Parton and the late Jimmy Stewart whose voice was featured in a Calm Christmas Sleep Story in 2023 thanks to generative AI technology. Goggins currently stars on “The White Lotus” where his character is often the most stressed out and tortured of the ensemble at one point setting a slew of snakes free.
“You have a government that is reckless about what is going to happen to Guyana” said Melinda Janki an international lawyer in Guyana who is handling several lawsuits against Exxon. It’s pursuing “a supposed course of development that is actually backward and destructive” she told CNN. kelpdao And while plenty of Guyanese people welcome the new oil industry some say Guyana’s startling economic statistics do not reflect a real-world prosperity for ordinary people many of whom are struggling with the higher prices accompanying the oil boom. Inflation rose 6.6 in 2023 with prices of some foods shooting up much more rapidly. “Since the oil extraction began in Guyana we have noticed that our cost of living has gone sky high” said Wintress White of Red Thread a non-profit that focuses on improving living conditions for Guyanese women. “The money is not trickling down to the masses” she told CNN. CNN contacted President Ali the Ministry of Natural Resources and the Ministry of Finance for comment but received no response. Guyana a former Dutch then British colony which gained independence in 1966 is one of only a handful of countries that is a “carbon sink” meaning it stores more planet-heating pollution than it produces. This is due to its vast rainforest; trees remove carbon dioxide from the atmosphere as they grow. The country has protected its biodiversity where others have destroyed theirs President Ali said in a BBC interview last year. In 2009 the country signed an agreement with Norway which promised Guyana more than 250 million to preserve its 18.5 million hectares or nearly 46 million acres of forests. Ali insists the country can balance climate leadership and fossil fuel exploitation. The new oil wealth will allow Guayana to develop including building climate adaptations such as sea walls he has said. He has also pointed to the continued failures of wealthy countries already grown rich on their own fossil fuels to help poorer countries with climate finance. But there are concerns Guyana could fall victim to the “resource curse” in which vast new wealth ?can actually make life worse for those who live there.
“Every morning I come downstairs and he’s already done the dishwasher he’s already packed his lunch and he’s ready to go” Ruthe’s father Ben tells CNN Sports. “He’s just a disciplined kid. He goes to bed early he looks after himself he eats well he looks after his sister. He’s just a good kid around the house in all ways really. We’re very lucky.” pendle Ruthe is next due to compete in the 1500 meters at the Maurie Plant Meet in Melbourne on Saturday and one target time to aim for will be his dad’s fastest time of 3:41.22 – three hundredths of a second faster than Ruthe’s current personal best. But he still has a way to go before he can call himself the most decorated runner in his family. Dad Ben and mom Jess are both former national champions who represented New Zealand on the world stage while his maternal grandparents won European championship medals for Great Britain. His grandmother Rosemary Stirling arguably had the most impressive achievement: an 800m Commonwealth Games title from 1970. Despite his family pedigree Ruthe was never under any pressure to take running seriously. His parents in fact didn’t allow him or his sister Daisy to train at all until they were 13 never wanting their identities to be tied solely to running. “It feels like it’s the right decision about now” says Ben. But as he gradually starts to realize his potential Ruthe when pushed admits to having big goals in the sport. “If I had to pick one thing definitely Olympic gold” he says. “I feel like that’s most runners’ dream and the biggest thing you can actually win. So that’ll definitely be the top of my bucket list.” The 2032 Olympics in Brisbane Ruthe adds would be a nice target. And as for the Los Angeles Games in three years’ time? “I’d actually love to try and qualify for LA 28” he says. “I feel like that’ll be a tough goal. But if I do that I’ll be really happy.” Already Ruthe’s name is being mentioned in the same breath as Norway’s Jakob Ingebrigtsen the most successful middle-distance of this generation. It was his record as the youngest-ever four-minute miler that Ruthe took last week and the New Zealander also beat Ingebrigtsen’s 1500m record for a 15-year-old earlier this year. Ingebrigtsen’s success Ruthe says has given him hope that he too can “have a good future” in the sport. But his biggest source of motivation comes not from the two-time Olympic champion but from those closest to him – his training group led by coach Craig Kirkwood and athlete Sam Tanner. The pair were instrumental in Ruthe’s recent mile time of 3:58.35 and it was five-time national champion Tanner who paced him perfectly around four laps of the track on his way to the record.